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柴胡皂苷D

分析標(biāo)準(zhǔn)品,HPLC≥98%

Saikosaponian D

CAS號(hào):20874-52-6

分子式:C42H68O13

分子量:780.98

MDLMFCD09028095

別名:柴胡皂苷 D;Saikosaponin BII; Saikosaponin b2 std.; Saikosaponian D; SAIKOSAPONINB2STANDARD; SaikosaponinD; (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galact

貨號(hào)

規(guī)格/參數(shù)/品牌

價(jià)格

貨期

YJ-B20150-20mg

分析標(biāo)準(zhǔn)品,HPLC≥98%

900.00

現(xiàn)貨

YJ-B20150-200mg

分析標(biāo)準(zhǔn)品,HPLC≥98%

2500.00

現(xiàn)貨

A10268-20mg

分析標(biāo)準(zhǔn)品,含量96.5%,可溯源

1700.00

現(xiàn)貨

產(chǎn)品介紹

熔點(diǎn):256- 259℃

沸點(diǎn):893.7℃ at 760 mmHg

比旋光度:(EtOH)+37

外觀:白色粉末

儲(chǔ)存條件:2-8℃

注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)(44)

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28. [IF=4.927] Linlin Yang et al."Drought Stress Stimulates the Terpenoid Backbone and Triterpenoid Biosynthesis Pathway to Promote the Synthesis of Saikosaponin in Bupleurum chinense DC. Roots."MOLECULES.2022 Jan;27(17):5470

27. [IF=3.911] Du  Jikun et al."Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K."Neurotox Res. 2022 Jan;:1-11

26. [IF=2.45] Li Shengyun et al."Establishment and Application of a Method for the Determination of Ganoderic Acid A."J Food Quality. 2020;2020:6621853

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22. [IF=3.375] Tian Gao et al."Use of Saikosaponin D and JNK inhibitor SP600125, alone or in combination, inhibits malignant properties of human osteosarcoma U2 cells."Am J Transl Res. 2019; 11(4): 2070–2080

21. [IF=4.36] Xiaojing Zhang et al."A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway."J Ethnopharmacol. 2022 Jan;283:114742

20. [IF=5.81] Cui  Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369

19. [IF=3.205] Min He et al."Simultaneous determination of multiple bioactive components of Bu-zhong-yi-qi-tang in rat tissues by LC–MS/MS: Application to a tissue distribution study."J Chromatogr B. 2017 Feb;1044-1045:177

18. [IF=3.396] Shi  Weiwei et al."Saikosaponin-d inhibits proliferation by up-regulating autophagy via the CaMKKβ–AMPK–mTOR pathway in ADPKD cells."Mol Cell Biochem. 2018 Dec;449(1):219-226

17. [IF=4.396] Xiaoman Chen et al."Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells."Mol Pharmaceut. 2018;15(11):4974–4984

16. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696

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14.  Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism." Molecules 21.5 (2016): 597.https:##doi.org/10.3390/molecules21050597

13.  Tian D-D, Wang W, Wang H-N, Sze SCW, Zhang Z-J. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules. 2016; 21(6):696. https:##doi.org/10.3390/molecules

12.  ,王猛猛,吳雨,陳文文,王之通,張磊陽(yáng),蔣健.補(bǔ)中益氣湯6個(gè)成分在大鼠體內(nèi)的藥代動(dòng)力學(xué)研究[J].遼寧中醫(yī)雜志,2020,47(11):159-163.

11.  楊夢(mèng)玲, 尤朋濤, 何麗珊,. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動(dòng)力學(xué)[J]. 中國(guó)中藥雜志, 2018, 43(18).

10.  趙昕彤, 辛國(guó), 辛宇,. 煎煮時(shí)間對(duì)柴胡中柴胡皂苷A和柴胡皂苷D含量的影響[J]. 人參研究, 2017.

9.  廖念, 龐雪, 周逸群,. 正交試驗(yàn)法優(yōu)選北柴胡麩炒工藝[J]. 中國(guó)藥師, 2017, 020(004):738-740.

8.  曹雪, 蔡廣知, 趙凌,. 基于復(fù)合質(zhì)量常數(shù)的北柴胡飲片等級(jí)評(píng)價(jià)[J]. 中國(guó)實(shí)驗(yàn)方劑學(xué)雜志, 2018(18).

7.  李英, 焦倩, 張?zhí)焯?/span>,. 基于地形因子的河北省北柴胡生態(tài)適宜性區(qū)劃研究[J]. 中國(guó)中藥雜志, 2017, 042(022):4402-4407.

6.  廖念  龐雪  周逸群 等. 北柴胡麩煨工藝的正交試驗(yàn)法優(yōu)選[J]. 時(shí)珍國(guó)醫(yī)國(guó)藥  2017(05):96-98.

5.  龐雪  廖念  周逸群 等. 不同炮制方法對(duì)北柴胡中柴胡皂苷含量的影響[J]. 時(shí)珍國(guó)醫(yī)國(guó)藥  2016(12):2906-2908.

4.  寧艷梅 楊秀娟 陳暉 張金保 楊韜 任遠(yuǎn).不同比例鱉血炮制柴胡制品中柴胡總皂苷含量測(cè)定與比較[J].中獸醫(yī)醫(yī)藥雜志 2019 38(05):9-13.

3.  辛國(guó)  趙昕彤  李文 等. 不同時(shí)間煎煮柴胡對(duì)五柴胡飲中柴胡皂苷含量及藥效學(xué)的影響[J]. 長(zhǎng)春中醫(yī)藥大學(xué)學(xué)報(bào)  2018(4):641-644.

2.  張娜, 晏旎, 周蒙恩,. 柴胡皂苷d對(duì)氧化應(yīng)激誘導(dǎo)的人肝星狀細(xì)胞活化后ROS形成及NLRP3炎性小體表達(dá)的影響[J]. 時(shí)珍國(guó)醫(yī)國(guó)藥, 2020(4):805-809.

1.  程玉鵬, 王洪月, 高寧,. 柴胡與其內(nèi)生真菌共培養(yǎng)的內(nèi)生真菌中柴胡總皂苷含量測(cè)定[J]. 化學(xué)工程師, 2018, v.32;No.279(12):23-25.

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